From January to April 2022, when the Omicron variant was . The waning protection from vaccines is why CDC recommends recent booster shots, and why its especially important for people at higher risk to stay up-to-date on boosters. Outcomes of Elderly Patients Hospitalized with the SARS-CoV-2 Omicron B.1.1.529 Variant: A Systematic Review. -. See this image and copyright information in PMC. Len TM, Dorabawila V, Nelson L, Lutterloh E, Bauer UE, Backenson B, Bassett MT, Henry H, Bregman B, Midgley CM, Myers JF, Plumb ID, Reese HE, Zhao R, Briggs-Hagen M, Hoefer D, Watt JP, Silk BJ, Jain S, Rosenberg ES. , The CDC says, during that same period of time in August, unvaccinated people were 11 times . Booster and additional primary dose COVID-19 vaccinations among adults aged 65 yearsUnited States, August 13, 2021November 19, 2021. For . But while hospitalizations are rising across the country, the states . CDC. PMC https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines.html. CDC COVID data tracker. , Since the vaccine rollout began last December, less than one third of 1% of fully vaccinated Garden State residents have tested positive for COVID, and of the more than 5 million people fully . Design, setting, and participants: The vaccines are not perfect, and the vast majority of vulnerable people have been vaccinated, so the small proportion who get seriously ill still amount to a lot of people. Through Monday, 81 per cent of adults 18-plus have received at least one dose, while 73.4 per cent of Ontario's adult population is fully vaccinated. Before Using representative data from 192 509 hospitalizations (see Table 1 for demographic information), monthly COVID-19-associated hospitalization rates ranged from 3.5 times to 17.7 times higher in unvaccinated persons than vaccinated persons regardless of booster dose status. Dr Anderson reported grants from Pfizer, Sanofi, GSK, Janssen, MedImmune, Regeneron, PaxVax, Micron, and Merck as well as personal fees from Moderna, Pfizer, Sanofi, GSK, Janssen, Medscape, Kentucky BioProcessing Inc, and WCG and ACI outside the submitted work; additionally, his institution has also received funding from the National Institutes of Health to conduct clinical trials of COVID-19 vaccines. New Jersey announced 25,277 new cases confirmed by PCR tests Tuesday, the seventh straight day with more than 20,000 new infections, and another 5,137 confirmed through antigen tests. Arthur Presnetsov, Adam Schiller, Vaccine Task Force, CDC COVID-19 Emergency Response Team. Four analysis periods were designated based on the threshold week when the weighted proportions of lineages from whole-genome sequencing results submitted to or performed by CDC: pre-Delta (April 4May 29, 2021: 0.1%7% proportion range), Delta emergence (May 30July 3, 2021: 14%69%), Delta predominance (July 4November 27, 2021: 81%99%), and Omicron emergence (November 28December 25, 2021: 1%72%). Younger Americans Benefited Less From Booster Shots Than Older People. endorsement of these organizations or their programs by CDC or the U.S. Fast HE, Zell E, Murthy BP, et al. The data from this chart come from the CDC, which collects data on the number of deaths by vaccination status from 30 health departments (including states and cities) across the country. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. On August 13, 2021, CDC recommended an additional Pfizer-BioNTech or Moderna primary series dose for persons moderately or severely immunocompromised (https://www.cdc.gov/media/releases/2021/s0813-additional-mRNA-mrna-dose.html). Accessed 1 Apr 2022. On September 24, 2021, CDC recommended a Pfizer-BioNTech booster dose for certain Pfizer-BioNTech primary series recipients, including all adults aged 65 years and persons aged 18 years in certain populations and high risk occupational and institutional settings (https://www.cdc.gov/media/releases/2021/p0924-booster-recommendations-.html). SARS-CoV-2 RNA Levels in Wastewater in the United States. Epub January 21, 2021. Nov 30, 2022. Bethesda, MD 20894, Web Policies Generic indicators of ecological resilience: inferring the chance of a critical transition. and/or the original MMWR paper copy for printable versions of official text, figures, and tables. Hospitalizations have quadrupled in one month from early December and intensive care admissions and ventilator use have each tripled in that time. adds wastewater data to its Covid-19 tracker. 2022 May;52(3):511-525. MMWR Morb Mortal Wkly Rep 2021;70:17359. For primary mRNA vaccination series, the vaccine product of the second dose was used to determine primary series product type. Although COVID-19 vaccine effectiveness decreased with emergence of the Delta variant and waning of vaccine-induced immunity, protection against hospitalization and death has remained high. The number of observations informing each CI reflects the number of weeks per period: OctoberNovember (7), and December (4). Corresponding author: Heather M. Scobie, vih8@cdc.gov. The Henry J. Kaiser Family Foundation Headquarters: 185 Berry St., Suite 2000, San Francisco, CA 94107 | Phone 650-854-9400 Effectiveness of COVID-19 mRNA vaccines against COVID-19associated hospitalizationfive Veterans Affairs medical centers, United States, February 1-August 6, 2021. References to non-CDC sites on the Internet are Rates of COVID-19 cases were lowest among fully vaccinated persons with a booster dose, compared with fully vaccinated persons without a booster dose, and much lower than rates among unvaccinated persons during OctoberNovember (25.0, 87.7, and 347.8 per 100,000 population, respectively) and December 2021 (148.6, 254.8, and 725.6 per 100,000 population, respectively) (Table 2). What are the implications for public health practice? A COVID-19 case in an unvaccinated person occurred when the person did not receive any FDA-authorized COVID-19 vaccine doses before the specimen collection date. 5.8% were fully vaccinated plus a booster shot. Isnt Publishing Large Portions of the Covid Data It Collects. The New York Times. Against omicron, however, the vaccines haventfaredas welland are much worse at preventing infection or mild disease. sharing sensitive information, make sure youre on a federal When accounting for total population and differences in the risk of severe disease among all ages, the rate of COVID-19-related hospitalization among those with at least two vaccine doses is 124.9 . Johnson & Johnson, which partly tested its vaccine in South Africa when the beta variant emerged, reported an efficacy of 66% in preventing moderate to severe COVID-19 and an efficacy of 85% in preventing severe or critical COVID-19in its clinical trial. However, the post claims that the death rate for vaccinated people is greater than the death rate . On August 13, 2021, CDC recommended an additional Pfizer-BioNTech or Moderna primary series dose for persons with moderately or severely immunocompromise. Exposures: Between August 12, 2021, and December 6, 2021, 10,236 ED encounters with a primary diagnosis of COVID-19 were observed. The CDC monitors rates of COVID-19 cases and deaths and laboratory-confirmed COVID-19 hospitalizations by vaccination status and age group, and publishes data and interactive tables on its website monthly, where anyone can download them. Each CI represents the remaining variation in observed weekly incidence rates and resulting incidence rate ratios. We take your privacy seriously. What is already known about this topic? HHS Vulnerability Disclosure, Help Second, this ecological study lacked multivariable adjustments, and causality could not be determined. Analysis periods for this table were designated based on robust reporting of cases among persons with booster doses from October 2021 and the threshold week when the weighted proportions of lineages from whole-genome sequencing results submitted to or performed by CDC: October 3November 27, 2021 (Delta predominance: 99%), and November 28December 25, 2021 (Omicron emergence: 1%72%). MMWR Morb Mortal Wkly Rep. 2022 Jan 28;71(4):125-131. doi: 10.15585/mmwr.mm7104e1. A survey of hospitals on Dec. 31 showed: The surge has prompted Health Commissioner Judy Persichilli to request reinforcements from the federal government. A COVID-19 case in a fully vaccinated person occurred when SARS-CoV-2 RNA or antigen was detected in a respiratory specimen collected 14 days after completing the primary series of a COVID-19 vaccine with FDA approval or emergency use authorization. 2023 Jan 25:10815589221149191. doi: 10.1177/10815589221149191. That page provides the underlying data for the agencys COVID Data Trackers comparison of COVID-19 cases and deaths by vaccination status. official website and that any information you provide is encrypted This is still a tiny fraction of the 168 million people who are vaccinated in the United . Overall, mortality rate was 12.2% (n = 53) and this was higher (16.2%, n = 39) in unvaccinated patients as compared to fully vaccinated patients (6.1%, n = 10, p-value 0.006). Variant proportions. part 46.102(l)(2), 21 C.F.R. By April 2022, the United States Centers for Disease Control and Prevention (CDC) data show that about 6 in 10 adults dying of COVID-19 were vaccinated or boosted, and thats remained true through at least August 2022 (the most recent month of data). At his weekly pandemic briefing on Monday, Gov. COVID-19-Associated Hospitalizations Among Adults During SARS-CoV-2 Delta and Omicron Variant Predominance, by Race/Ethnicity and Vaccination Status - COVID-NET, 14 States, July 2021-January 2022. Alabama, Arkansas, California, Colorado, District of Columbia, Florida, Georgia, Idaho, Indiana, Kansas, Louisiana, Massachusetts, Michigan, Minnesota, Nebraska, New Jersey, New Mexico, New York, New York City (New York), Rhode Island, Seattle/King County (Washington), Tennessee, Texas, Utah, and Wisconsin. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Disclaimer. And thats not correct. Covid-19 rates by time since vaccination during Delta variant predominance. CDC charts show how much 2 and 3 doses of COVID vaccine protect from hospitalization. Vaccine effectiveness of primary series and booster doses against Omicron variant COVID-19associated hospitalization in the United States. On November 19, 2021, and November 29, 2021, CDC expanded recommendations for booster doses to include all adults aged 18 years (https://www.cdc.gov/media/releases/2021/s1119-booster-shots.html, https://www.cdc.gov/media/releases/2021/s1129-booster-recommendations.html). A COVID-19associated death occurred in a person with a documented COVID-19 diagnosis who died, and whose report local health authorities reviewed (e.g., using vital records, public health investigation, or other data sources) to make that determination. Protection improved among persons who received a booster dose compared with not receiving a booster, regardless of primary series vaccine product type. Weekly COVID-19 cases (April 4December 25, 2021) and associated deaths (April 4December 4, 2021) by vaccination status, including additional and booster doses starting October 3, were reported from 25 state and local health departments that routinely link case surveillance to vaccination data from immunization registries; 2- and 5-week reporting lag times for cases and deaths, respectively, allowed for more complete reporting, data linkage, and mortality ascertainment. For instance, a Centers for Disease Control and Prevention study. Phil Murphy said hewants to increase the capacity at some hospitals by 50to 100 beds indoorsor in tents on their campus,and not in a field station like one established at the Meadowlands convention center in 2020. Per national guidance, this should include persons whose death certificate lists COVID-19 disease or SARS-CoV-2 as an underlying cause of death or as a significant condition contributing to death. The data also showed vaccine effectiveness against severe infection remained high, with just 4.59 fully vaccinated adults out of 100,000 being hospitalized with COVID-19 in the week of Dec. 27 . Persichilli has said that the bulk of COVID patients in the state's hospitals about 70% are unvaccinated. Posted August 29, 2021. doi: 10.1101 . During 2021, averaged weekly, age-standardized case IRRs among unvaccinated persons compared with fully vaccinated persons decreased from 13.9 pre-Delta to 8.7 as Delta emerged, and to 5.1 during the period of Delta predominance. Townhall weekly columnist. URL addresses listed in MMWR were current as of analysis posted on the Peterson-KFF Health System Tracker, unvaccinated people are at much greater risk of death, 14% of adults overall and 31% of older adults (65 years and older) have received the latest bivalent boosters. Eligible persons should stay up to date with COVID-19 vaccinations. To assess the impact of full vaccination with additional and booster doses (booster doses), case and death rates and incidence rate ratios (IRRs) were estimated among unvaccinated and fully vaccinated adults by receipt of booster doses during pre-Delta (AprilMay 2021), Delta emergence (June 2021), Delta predominance (JulyNovember 2021), and Omicron emergence (December 2021) periods in the United States. Older people are at greater risk for severe illness and death from COVID-19 than younger people, but vaccines and boosters still lower that risk substantially. Among all COVID deaths in the weeks leading up through Aug. 30, just 97 were fully vaccinated people who contracted breakthrough cases of the coronavirus. Results: Using representative data from 192 509 hospitalizations (see Table 1 for demographic information), monthly COVID-19-associated hospitalization rates ranged from 3.5 times to 17.7 times higher in unvaccinated persons than vaccinated persons regardless of booster dose status. 2023 Jan 9;20(2):1182. doi: 10.3390/ijerph20021182. Peaks in age-standardized case and death rates occurred during August (>95% of infections attributed to the Delta variant); case rates also peaked during the 2 weeks ending December 18 and 25 (39% and 72% infections attributed to the Omicron variant, respectively) (Figure). COVID hospitalization in NJ reach 8-month high. Expert groups continue to recommend use of the drug during pregnancy when necessary and in consultation with a doctor. State immunization information system data were linked to cases, and the vaccination coverage data of the defined catchment population were used to compare hospitalization rates in unvaccinated and vaccinated individuals. CDC. MMWR Morb Mortal Wkly Rep 2021;70:128490. Substantial case rate increases were recorded among unvaccinated and vaccinated persons when Omicron became the predominant variant in December, resulting in decreased IRRs and declining crude VE estimates (7). On September 24, 2021, CDC recommended a Pfizer-BioNTech booster dose for certain Pfizer-BioNTech primary series recipients, including all adults aged 65 years and persons aged 18 years in certain populations and high risk occupational and institutional settings. CDC, public affairs specialist. Cases were excluded in partially vaccinated persons who received at least one FDA-authorized or approved vaccine dose but did not complete a primary series 14 days before collection of a respiratory specimen with SARS-CoV-2 RNA or antigen detected. In particular, the story said the CDC left out data on the effectiveness of boosters in people ages 18 to 49. Similarly, to be counted as having a booster, a person must be at least two weeks out from their booster or additional dose before testing positive. The overall crude incidence rates for pneumonia-related-hospitalization and mortality were 1.12 and 0.09 per 1000 patient-years, respectively (Table 2). Anthes, Emily. No other disclosures were reported. The .gov means its official. Fully vaccinated COVID-19 hospital patients had an aOR of 0.33 for death or the need for invasive mechanical ventilation. Comparing unvaccinated persons with fully vaccinated persons without a booster dose, age-standardized case IRRs during OctoberNovember and December were 4.0 and 2.8 respectively, representing decreases in VE from 75% to 64%. A spokesperson for the CDC, Kristen Nordlund, told the New York Times the agency has been slow to release some data because its not ready for prime time and because of the fear that it could be misinterpreted. [A]lthough rooted in the contention that the agency isnt being nearly as straightforward or transparent or comprehensive as they need to be, my tweet could be interpreted as misleading and thats the absolute last thing I want to do so Ive removed it, he wrote. Editors note:SciChecks COVID-19/Vaccination Projectis made possible by a grant from the Robert Wood Johnson Foundation. The CDC data show that about 95% of adults who died from COVID-19 in 2022 in these jurisdictions were over age 50, and about 8 in 10 were age 65 or older, underscoring the need for older adults to stay up-to-date on recommended booster shots. No other potential conflicts of interest were disclosed. Data from the Centers for . "If we don't have the medical staff to go out there and take care of patients, it's really going to be all for naught," Callahan said Monday. Despite more breakthrough cases, unvaccinated patients still make up the majority of COVID hospitalizations, according to data from the New Jersey Hospital Association. Last updated 24 Mar 2022. Per national guidance, this should include persons whose death certificate lists COVID-19 disease or SARS-CoV-2 as an underlying cause of death or as a significant condition contributing to death. Murphy deflecting (Opinion), More Murphy hypocrisy: Save NJ bears but let the whales die (Opinion), NJ subreddit users have some choice words for Gov. and new hospitalizations with laboratory-confirmed COVID-19 among fully vaccinated and unvaccinated adults, and estimated vaccine effectiveness . Health department officials have not said where the extra staffers will be deployed. Balian S, Bailey B, Abboud S, Kim Y, Humphries D, Kambali S, Kalangi ST, Jarvis J, Dayal L, Beiz H, Battisti R, Haddad N. J Investig Med. Because of reporting lags, the influence of the Omicron variant on COVID-19associated deaths by vaccination status in December could not be evaluated. On January 21, 2022, this report was posted online as an MMWR Early Release. The state previously said 49 fully vaccinated people in New Jersey died of the . MMWR and Morbidity and Mortality Weekly Report are service marks of the U.S. Department of Health and Human Services. President Joe Biden visited Somerset County on Tuesday, Sept. 7, 2021, for a meeting with state and county officials in Hillsborough and a tour of storm damage in Manville. Booster shots arerecommendedfor most people, as theseincrease and prolongprotection against severe disease and also provide some temporary protection against infection and milder illness. The C.D.C. 33.6% were "under-vaccinated," meaning they either received only one shot of the Pfizer or Moderna vaccine, or have not received a booster shot. According to this data, for example, unvaccinated people over 5 years old were 2.4 times more likely to test positive for COVID-19 and 9 times more likely to die from COVID-19 in January. Phil Murphy. Some 73.3% of hospitalized COVID patients are unvaccinated; 23.7% are fully vaccinated; and 3% are partially vaccinated. 8600 Rockville Pike To subscribe via email notifications, you must first sign in. Data shown for individuals vaccinated with a booster for the following dates: adults 18 years and older (age adjusted), October 30, 2021, to April 30, 2022 (A), age 18 to 49 years, November 27, 2021, to April 30, 2022 (B), age 50 to 64 years, November 6, 2021, to April 30, 2022 (C), and 65 years or older, October 16 to April 30, 2022 (D). To determine characteristics of COVID-19-associated hospitalizations among vaccinated persons and comparative hospitalization rates in unvaccinated and vaccinated persons. But by January 2022, as we showed in an analysis posted on the Peterson-KFF Health System Tracker, about 4 in 10 deaths were vaccinated or boosted. You may Update this view or Save a new view to see your changes, or Cancel to stay on this page. Posted online June 14, 2022. . MMWR Morb Mortal Wkly Rep. 2021;70(44):1545-1552. doi:10.15585/mmwr.mm7044e2 The Moderna vaccineshowed similar results in its clinical trial, with afinalefficacy of93%. Hospitalizations had peakedat 8,270on April 15, 2020. Average weekly incidences and rate ratios are provided by age group, primary series vaccine type, and overall; overall and vaccine-specific rates were standardized by age, according to the enumerated 2000 U.S. Census age distribution. 2023 Jan 26;12(3):961. doi: 10.3390/jcm12030961. mmwrq@cdc.gov. Analysis periods were categorized as April 4May 29, 2021 (pre-Delta: 0.1%7% proportion range), May 30July 3, 2021 (Delta emergence: 14%69%), July 4November 27, 2021 (Delta predominance: 81%99%), and November 28December 25, 2021, (Omicron emergence: 1%72%). This conversion might result in character translation or format errors in the HTML version. Credit: Amanda Montaez; Source: Centers for Disease Control and Prevention. Average weekly incidence rates and rate ratios are provided by age group, primary series vaccine type, and overall; overall and vaccine-specific rates were standardized by age, according to the enumerated 2000 U.S. Census age distribution. Isnt Publishing Large Portions of the Covid Data It Collects. 31 Mar 2022. CDC twenty four seven. Understanding risk factors for hospitalization in vaccinated persons and the association of COVID-19 vaccines with hospitalization rates is critical for public health efforts to control COVID-19. Pediatric cases ticked up from 1.13% in the first three months of 2021 to 1 . Among these, encounters discharged from the ED, fully vaccinated but not . Fericean RM, Oancea C, Reddyreddy AR, Rosca O, Bratosin F, Bloanca V, Citu C, Alambaram S, Vasamsetti NG, Dumitru C. Int J Environ Res Public Health. Protection against infection and death during the Delta-predominant period and against infection during Omicron emergence were higher among booster vaccine dose recipients, especially among persons aged 5064 and 65 years. Fourth, variable data linkage completeness might have resulted in misclassifications (e.g., booster doses not being linked to primary series) that could influence IRR estimates (5). meets with refugee families. CDC and other researchers have shown that protection from COVID-19 vaccines can diminish, or wane, over time and booster doses are needed to maintain a robust immune response. However, the rising share of the population that is vaccinated is only part of the story and does not seem to explain all of the rise in the share of deaths that are among vaccinated people over the last year. ** Reporting is by primary series vaccine type rather than additional or booster dose vaccine type. The agency has not communicated any intention to discontinue these publications. Although COVID-19 vaccine effectiveness decreased with emergence of the Delta variant and waning of vaccine-induced immunity, protection against hospitalization and death has remained high. The SARS-CoV-2 B.1.1.529 (Omicron) variant emerged in the United States during December 2021 (6) and by December 25 accounted for 72% of sequenced lineages (7). Jan 28, 2022, 4:39 AM. COVID-19 vaccines are highly effective at preventing severe disease, hospitalization, and death [] So whats going on here? CDC and other researchers have shown boosters are highly effective in preventing hospitalizations and deaths, including among those most vulnerable to COVID-19. You have unsaved data that will be lost if you leave this page. 4 Feb 2022. With the Omicron variant, combined with a reduction in other preventive measures like masking, vaccinated people may be more likely to be infected than they were this time last year. All information these cookies collect is aggregated and therefore anonymous. MMWR Morb Mortal Wkly Rep. 2022 Mar 25;71(12):466-473. doi: 10.15585/mmwr.mm7112e2. Scobie HM, Johnson AG, Suthar AB, et al. A COVID-19 case in a fully vaccinated person occurred when SARS-CoV-2 RNA or antigen was detected in a respiratory specimen collected 14 days after completing the primary series of a COVID-19 vaccine with FDA approval or emergency use authorization.